Affiliation:
1. Universidade Federal de Pernambuco, Brazil
2. Universidade Federal de São Paulo, Brazil
Abstract
SUMMARY In this brief communication we describe the occurrence of a KPC-producing Serratia marcescensisolate in a home-care patient from Recife, Brazil. The blaKPC, blaSPM, blaIMP, blaVIMblaOXA, blaCTX-M, blaSHV, blaTEM and blaGES genes were investigated by Polymerase Chain Reaction (PCR) and DNA sequencing. The isolate was positive for blaKPC-2 and blaTEM-1 and was resistant to aztreonam, cefepime, cefotaxime, imipenem, meropenem, gentamicin, ciprofloxacin and cefazidime, and susceptible only to amikacin, tigecycline and gatifloxacin. This is the first report in Brazil of KPC-producing S. marcescens clinical isolate outside of a hospital environment. Caregivers should be alert for the presence of this isolate in the community setting.
Subject
Infectious Diseases,General Medicine
Reference18 articles.
1. First report of investigation into an outbreak due to carbapenemase-producing Klebsiella pneumoniae in a tertiary Brazilian hospital, with extension to a patient in the community;Abboud CS;J Infect Prev,2011
2. Dissemination of blaKPC-2by the spread of Klebsiella pneumoniae clonal complex 258 clones (ST258, ST11, ST437) and plasmids (IncFII, IncN, IncL/M) among Enterobacteriaceae species in Brazil;Andrade LN;Antimicrob Agents Chemother,2011
3. Multidrug resistance genes, including bla(KPC) and bla(CTX)-M-2, among Klebsiella pneumoniae isolated in Recife, Brazil;Cabral AB;Rev Soc Bras Med Trop,2012
4. Emergence of Serratia marcescens,Klebsiella pneumoniae, and Escherichia coli isolates possessing the plasmid-mediated carbapenem-hydrolyzing beta-lactamase KPC-2 in intensive care units of a Chinese hospital;Cai JC;Antimicrob Agents Chemother,2008
5. Overview of the epidemiology and the threat of Klebsiella pneumoniae carbapenemase (KPC) resistance;Chen LF;Infect Drug Resist,2012
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