Errors in medicine administration - profile of medicines: knowing and preventing

Author:

Reis Adriano Max Moreira1,Marques Tatiane Cristina2,Opitz Simone Perufo3,Silva Ana Elisa Bauer de Camargo4,Gimenes Fernanda Raphael Escobar5,Teixeira Thalyta Cardoso Alux2,Lima Rhanna Emanuela Fontenele2,Cassiani Silvia Helena De Bortoli2

Affiliation:

1. Federal University of Minas Gerais, Brazil

2. University of São Paulo, Brazil

3. Federal University of Acre, Brazil

4. Federal University of Goiás, Brazil

5. Camilo Castelo Branco University

Abstract

OBJECTIVES: To describe the pharmacological characteristics of medicines involved in administration errors and determine the frequency of errors with potentially dangerous medicines and low therapeutic index, in clinical units of five teaching hospitals, in Brazil. METHODS: Multicentric study, descriptive and exploratory, using the non-participant observation technique (during the administration of 4958 doses of medicines) and the anatomical therapeutic chemical classification (ATC). RESULTS: Of that total, 1500 administration errors were identified (30.3%). The administration of pharmacological groups - ATC (cardiovascular system, nervous system, alimentary tract and metabolism system and anti-infectives for systemic use) showed a higher frequency of errors. In 13.0% of errors were involved potentially dangerous medicines and in 12.2% medicines with low therapeutic index. CONCLUSION: The knowledge of the pharmacological profile could be an important strategy to be used in the prevention medication errors in health institutions.

Publisher

FapUNIFESP (SciELO)

Subject

Advanced and Specialized Nursing,Medical–Surgical Nursing

Reference29 articles.

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2. Preventing medication errors: a summary;Bates DW;Am J Health Syst Pharm.,2007

3. Crossing the quality chasm: a new health system for the 21st century,2001

4. Preventing adverse drug events in hospital practice: an overview;Rommers MK;Pharmacoepidemiol Drug Saf,2007

5. Preventing medication errors: quality chasm series;Aspden P,2007

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