Synthesis and molecular modelling studies of pyrimidinones and pyrrolo[3,4-d]-pyrimidinodiones as new antiplasmodial compounds

Author:

Rogerio Kamilla Rodrigues1,Carvalho Leonardo J M2,Domingues Luiza Helena Pinto1,Neves Bruno Junior3,Moreira Filho José Teófilo4,Castro Rosane Nora1,Bianco Júnior Cesare2,Daniel-Ribeiro Claudio Tadeu2,Andrade Carolina Horta5,Graebin Cedric Stephan1

Affiliation:

1. Universidade Federal Rural do Rio de Janeiro, Brasil

2. Fundação Oswaldo Cruz-Fiocruz, Brasil

3. Universidade Federal de Goiás, Brasil; Centro Universitário de Anápolis, UniEvangélica, Brasil

4. Universidade Federal de Goiás, Brasil

5. Universidade Federal de Goiás, Brasil; Universidade de Campinas, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Microbiology (medical)

Reference47 articles.

1. New molecular targets and strategies for antimalarial discovery;Aguiar AC;Curr Med Chem,2017

2. Successful treatment of Plasmodium falciparum malaria with a six-dose regimen of artemether-lumefantrine versus quinine-doxycycline in the Western Amazon region of Brazil;Alecrim MG;Am J Trop Med Hyg,2006

3. Oral artesunate dose-response relationship in acute falciparum malaria;Angus BJ;Antimicrob Agents Chemother,2002

4. UniProt: the universal protein knowledgebase;Apweiler R;Nucleic Acids Res,2004

5. Integrated Modeling Program, Applied Chemical Theory (IMPACT);Banks JL;J Comput Chem,2005

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