Affiliation:
1. 1 University of Szeged Department of Medical Microbiology and Immunobiology Szeged Hungary
Abstract
Mycobacterium smegmatisis a species of rapidly growing saprophytes with a number of properties that make it an effective vaccine vector. RecombinantM. smegmatisexpressing protective antigens of different pathogens and molecules modulating the immune responses offers some potential for reduction of the burden of tuberculosis, HIV and hepatitis B infections. This paper discusses the molecular methods used to generate recombinantM. smegmatisand the results obtained with some of these recombinants.
Subject
General Immunology and Microbiology,General Medicine
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