Modeling of the effect of bio-conjugation to anti-interleukin-10 antibodieson the photoluminescence of CdSe/ZnS quantum dots

Abstract

ABSTRACTBio-conjugated CdSe/ZnS core/shell quantum dots (QDs) attract essential scientific interest due to their possible nano-medicine applications, including selective highlighting of affected tissues and targeted drug delivery to the certain type of cells. The paper is focused on the theoretical description of the blue shift observed in the luminescence spectra of CdSe/ZnS QDs upon their bio-conjugation with the anti-interleukin-10 antibodies. We propose a model that describes the ground state of the exciton confined in a quantum dot and explaining the bio-conjugation phenomenon by the change of the effective confinement volume.