Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies-Reference-Cited by-同舟云学术

Nondisplaceable Binding Is a Potential Confounding Factor in 11C-PBR28 Translocator Protein PET Studies

Published:2020-07-17 Issue:3 Volume:62 Page:412-417
ISSN:0161-5505
Container-title:Journal of Nuclear Medicine
language:en
Short-container-title:J Nucl Med

Author:

Laurell Gjertrud L.,Plavén-Sigray Pontus,Jucaite Aurelija,Varrone Andrea,Cosgrove Kelly P.,Svarer Claus,Knudsen Gitte M.,Ogden R. Todd,Zanderigo Francesca,Cervenka Simon,Hillmer Ansel T.,Schain Martin,

Publisher

Society of Nuclear Medicine

Subject

Radiology, Nuclear Medicine and imaging

Reference35 articles.

1. The 18 kDa Translocator Protein, Microglia and Neuroinflammation

2. Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios;Fujita;EJNMMI Res.,2017

3. Two Binding Sites for [3H]PBR28 in Human Brain: Implications for TSPO PET Imaging of Neuroinflammation

4. An 18-kDa Translocator Protein (TSPO) Polymorphism Explains Differences in Binding Affinity of the PET Radioligand PBR28

5. Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data

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