Gain-of-Function Mutations in the Toll-Like Receptor Pathway: TPL2-Mediated ERK1/ERK2 MAPK Activation, a Path to Tumorigenesis in Lymphoid Neoplasms?
Author:
Funder
Canadian Institutes of Health Research
Fonds de Recherche du Québec - Santé
Publisher
Frontiers Media SA
Subject
Cell Biology,Developmental Biology
Reference61 articles.
1. Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma;Ansell;Blood Cancer J.,2014
2. Activation of lymphoma-associated MyD88 mutations via allostery-induced TIR-domain oligomerization;Avbelj;Blood,2014
3. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells;Banerjee;Proc. Natl. Acad. Sci. U.S.A.,2006
4. Lipopolysaccharide activation of the TPL-2/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase cascade is regulated by IkappaB kinase-induced proteolysis of NF-kappaB1 p105;Beinke;Mol. Cell. Biol.,2004
5. The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1;Buxadé;Immunity,2005
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