Degradation and Transmission of Tau by Autophagic-Endolysosomal Networks and Potential Therapeutic Targets for Tauopathy
Author:
Funder
National Institutes of Health
Publisher
Frontiers Media SA
Subject
Cellular and Molecular Neuroscience,Molecular Biology
Reference129 articles.
1. Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes.;Andersson;Sci. Rep.,2019
2. Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer’s brains.;Ando;Acta Neuropathol.,2013
3. Level of PICALM, a key component of clathrin-mediated endocytosis, is correlated with levels of phosphotau and autophagy-related proteins and is associated with tau inclusions in AD, PSP and Pick disease.;Ando;Neurobiol. Dis.,2016
4. Depletion of microglia and inhibition of exosome synthesis halt tau propagation.;Asai;Nat. Neurosci.,2015
5. Tau phosphorylation in hippocampus results in toxic gain-of-function.;Avila;Biochem. Soc. Trans.,2010
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