Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes-Reference-Cited by-同舟云学术

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Antibody-mediated clearance of tau in primary mouse microglial cultures requires Fcγ-receptor binding and functional lysosomes

Published:2019-03-15 Issue:1 Volume:9 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Andersson Christian Rungsted,Falsig Jeppe,Stavenhagen Jeffrey B.,Christensen Søren,Kartberg Fredrik,Rosenqvist Nina,Finsen Bente,Pedersen Jan Torleif

Funder

Innovation Fund Denmark, H. Lundbeck A/S

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-019-41105-4.pdf

Reference44 articles.

1. Clavaguera, F. et al. Transmission and spreading of tauopathy in transgenic mouse brain. Nat Cell Biol. 11, 909–913 (2009).

2. Hanger, D. P., Anderton, B. H. & Noble, W. Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 15, 112–119 (2009).

3. Spires-Jones, T. L., Stoothoff, W. H., de Calignon, A., Jones, P. B. & Hyman, B. T. Tau pathophysiology in neurodegeneration: a tangled issue. Trends Neurosci. 32, 150–9 (2009).

4. Ballatore, C., Lee, V. M.-Y. & Trojanowski, J. Q. Tau-mediated neurodegeneration in Alzheimer’s disease and related disorders. Nat. Rev. Neurosci. 8, 663–72 (2007).

5. Brion, J. P., Octave, J. N. & Couck, A. M. Distribution of the phosphorylated microtubule-associated protein tau in developing cortical neurons. Neuroscience 63, 895–909 (1994).

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