Elucidation of Arctigenin Pharmacokinetics and Tissue Distribution after Intravenous, Oral, Hypodermic and Sublingual Administration in Rats and Beagle Dogs: Integration of In Vitro and In Vivo Findings-Reference-Cited by-同舟云学术

Elucidation of Arctigenin Pharmacokinetics and Tissue Distribution after Intravenous, Oral, Hypodermic and Sublingual Administration in Rats and Beagle Dogs: Integration of In Vitro and In Vivo Findings

Published:2017-06-14 Issue: Volume:8 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Li Jie,Li Xin,Ren Yu-Shan,Lv Yuan-Yuan,Zhang Jun-Sheng,Xu Xiao-Li,Wang Xian-Zhen,Yao Jing-Chun,Zhang Gui-Min,Liu Zhong

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference26 articles.

1. Plasma protein binding of amphotericin B and pharmacokinetics of bound versus unbound amphotericin B after administration of intravenous liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate.;Bekersky;Antimicrob. Agents Chemother.,2002

2. Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-alpha inhibition.;Cho;Int. Immunopharmacol.,2004

3. Hydrolysis is the dominating in vivo metabolism pathway for arctigenin: identification of novel metabolites of arctigenin by LC/MS/MS after oral administration in rats.;Gao;Planta Med.,2013

4. Elucidation of arctigenin pharmacokinetics after intravenous and oral administrations in rats: integration of in vitro and in vivo findings via semi-mechanistic pharmacokinetic modeling.;Gao;AAPS J.

5. Extensive intestinal first-pass metabolism of arctigenin: evidenced by simultaneous monitoring of both parent drug and its major metabolites.;Gao;J. Pharm. Biomed. Anal.

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