Extensive intestinal first-pass metabolism of arctigenin: Evidenced by simultaneous monitoring of both parent drug and its major metabolites
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Spectroscopy,Drug Discovery,Pharmaceutical Science,Analytical Chemistry
Reference43 articles.
1. Tumour-growth inhibiting substances of plant origin. 2. Experimental animal tumour-pharmacology of arctigenin-mustard;Dombradi;Chemotherapy,1970
2. Identification of arctigenin as an antitumor agent having the ability to eliminate the tolerance of cancer cells to nutrient starvation;Awale;Cancer Res.,2006
3. Induction of apoptosis of the human leukemia cells by arctigenin and its mechanism of action;Wang;Chin. J. Chem.,2008
4. Inhibition of angiogenesis: a novel antitumor mechanism of the herbal compound arctigenin;Gu;Anticancer Drugs,2013
5. Isolation, structure elucidation and bioactivity of schischkiniin, a unique indole alkaloid from the seeds of Centaurea schischkinii;Shoeb;Tetrahedron,2005
Cited by 9 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Simultaneous quantification of arctigenin and its glucuronide conjugate in mouse plasma using ultra‐high performance liquid chromatography coupled to tandem mass spectrometry;Journal of Separation Science;2021-01-14
2. Overview of the anti-inflammatory effects, pharmacokinetic properties and clinical efficacies of arctigenin and arctiin from Arctium lappa L;Acta Pharmacologica Sinica;2018-04-26
3. An on-chip intestine-liver model for multiple drugs absorption and metabolism behavior simulation;Science China Chemistry;2017-12-27
4. Dibenzylbutyrolactone Lignans – A Review of Their Structural Diversity, Biosynthesis, Occurrence, Identification and Importance;Mini-Reviews in Medicinal Chemistry;2017-07-07
5. Elucidation of Arctigenin Pharmacokinetics and Tissue Distribution after Intravenous, Oral, Hypodermic and Sublingual Administration in Rats and Beagle Dogs: Integration of In Vitro and In Vivo Findings;Frontiers in Pharmacology;2017-06-14
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3