Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats-Reference-Cited by-同舟云学术

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Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats

Published:2019-06-13 Issue: Volume:10 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Zhang Ziqian,Liu Dandan,Jiang Jianwei,Song Xiuyun,Zou Xiaowen,Chu Shifeng,Xie Kebo,Dai Jungui,Chen Naihong,Sheng Li,Li Yan

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference44 articles.

1. Quantitative characterization of major hepatic UDP-glucuronosyltransferase enzymes in human liver microsomes: comparison of two proteomic methods and correlation with catalytic activity;Achour;Drug Metab. Dispos.,2017

2. Oxidative/nitrosative stress in rats subjected to focal cerebral ischemia/reperfusion;Awooda;Int. J. Health Sci. (Qassim),2015

3. Roles of human UDP-glucuronosyltransferases in clearance and homeostasis of endogenous substrates, and functional implications;Bock;Biochem. Pharmacol.,2015

4. Upregulating the expression of survivin-HBXIP complex contributes to the protective role of IMM-H004 in transient global cerebral ischemia/reperfusion;Chu;Mol. Neurobiol.,2017

5. Investigation of UDP-glucuronosyl transferases (UGTs) inhibitory properties of carvacrol;Dong;Phytother. Res.,2012

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The Active Glucuronide Metabolite of the Brain Protectant IMM-H004 with Poor Blood–Brain Barrier Permeability Demonstrates a High Partition in the Rat Brain via Multiple Mechanisms;Pharmaceutics;2024-02-27

2. Celastrol exerts a neuroprotective effect by directly binding to HMGB1 protein in cerebral ischemia–reperfusion;Journal of Neuroinflammation;2021-08-09

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