In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5-Reference-Cited by-同舟云学术

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In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5

Published:2018-04-05 Issue: Volume:9 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Beggiato Sarah,Borelli Andrea C.,Tomasini Maria C.,Castelli M. Paola,Pintori Nicholas,Cacciaglia Roberto,Loche Antonella,Ferraro Luca

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference46 articles.

1. Metabotropic glutamate receptor 5 negative modulation in phase I clinical trial: potential impact of circadian rhythm on the neuropsychiatric adverse reactions-do hallucinations matter?;Abou Farha;ISRN Psychiatry,2014

2. GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor.;Beggiato;Synapse,2013

3. Quantitative analysis reveals multiple mechanisms of allosteric modulation of the mGlu5 receptor in rat astroglia.;Bradley;Mol. Pharmacol.,2011

4. The mGluR5 antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) potentiates PCP-induced cognitive deficits in rats.;Campbell;Psychopharmacology (Berl.),2004

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. GET73 modulates lipopolysaccharide- and ethanol-induced increase in cytokine/chemokine levels in primary cultures of microglia of rat cerebral cortex;Pharmacological Reports;2024-08-01

2. The novel peptide LCGM-10 attenuates metabotropic glutamate receptor 5 activity and demonstrates behavioral effects in animal models;Frontiers in Behavioral Neuroscience;2024-02-07

3. The metabotropic glutamate receptor 5 as a biomarker for psychiatric disorders;International Review of Neurobiology;2023

4. Novel Agents for the Pharmacological Treatment of Alcohol Use Disorder;Drugs;2022-02

5. An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder;Psychopharmacology;2021-11-03

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