TAK-442, a Direct Factor Xa Inhibitor, Inhibits Monocyte Chemoattractant Protein 1 Production in Endothelial Cells via Involvement of Protease-Activated Receptor 1-Reference-Cited by-同舟云学术

TAK-442, a Direct Factor Xa Inhibitor, Inhibits Monocyte Chemoattractant Protein 1 Production in Endothelial Cells via Involvement of Protease-Activated Receptor 1

Published:2018-12-04 Issue: Volume:9 Page:
ISSN:1663-9812
Container-title:Frontiers in Pharmacology
language:
Short-container-title:Front. Pharmacol.

Author:

Shinozawa Emiko,Nakayama Masaharu,Imura Yoshimi

Funder

Takeda Pharmaceutical Company

Publisher

Frontiers Media SA

Subject

Pharmacology (medical),Pharmacology

Reference26 articles.

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3. Genetic evidence that protease-activated receptors mediate factor Xa signaling in endothelial cells.;Camerer;J. Biol. Chem.,2002

4. Discovery of a novel, orally active himbacine-based thrombin receptor antagonist (SCH 530348) with potent antiplatelet activity.;Chackalamannil;J. Med. Chem.,2008

5. Factor Xa and thrombin evoke additive calcium and proinflammatory responses in endothelial cells subjected to coagulation.;Daubie;Biochim. Biophys. Acta,2006

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