Impact of kinase activating and inactivating patient mutations on binary PKA interactions
Author:
Funder
Austrian Science Fund
Publisher
Frontiers Media SA
Subject
Pharmacology (medical),Pharmacology
Reference52 articles.
1. One single signaling pathway for so many different biological functions: lessons from the cyclic adenosine monophosphate/protein kinase A pathway-related diseases;Assié;J. Clin. Endocrinol. Metab.,2012
2. Reciprocal regulation of PKA and Rac signaling;Bachmann;Proc. Natl. Acad. Sci. U.S.A.,2013
3. Beta-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi;Baillie;Proc. Natl. Acad. Sci. U.S.A.,2003
4. Mutations in regulatory subunit type 1A of cyclic adenosine 5′-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes;Bertherat;J. Clin. Endocrinol. Metab.,2009
5. Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome;Beuschlein;N. Engl. J. Med.,2014
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