Author:
Hui Siwen,Kan Wen,Qin Shuanglin,He Ping,Zhao Jia,Li Hui,Bai Jun,Wen Jincai,Mou Wenqing,Hou Manting,Wei Ziying,Lin Li,Xiao Xiaohe,Xu Guang,Bai Zhaofang
Abstract
Graphical AbstractGUP can effectively inhibit the activation of cGAS-STING pathway induced by multiple stimuli and reduce the expression of type I interferon and pro-inflammatory cytokines. Meanwhile GUP also has a good therapeutic effect on sepsis contributed to cecum ligation and puncture.