Author:
Xu Ke-Xin,Xue Meng-Ge,Li Zhimin,Ye Bang-Ce,Zhang Bin
Abstract
Arbutin is a hydroquinone glucoside and a natural product present in various plants. Arbutin potently inhibits melanin formation. This property has been exploited in whitening cosmetics and pharmaceuticals. Arbutin production relies mainly on chemical synthesis. The multi-step and complicated process can compromise product purity. With the increasing awareness of sustainable development, the current research direction prioritizes environment-friendly, biobased arbutin production. In this review, current strategies for arbutin production are critically reviewed, with a focus on plant extraction, chemical synthesis, biotransformation, and microbial fermentation. Furthermore, the bottlenecks and perspectives for future direction on arbutin biosynthesis are discussed.
Funder
Major Discipline Academic and Technical Leaders Training Program of Jiangxi Province
Natural Science Foundation of Jiangxi Province
National Natural Science Foundation of China
Subject
Biomedical Engineering,Histology,Bioengineering,Biotechnology
Cited by
17 articles.
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