Author:
Wu Kaimin,He Xuliang,Wang Jinglei,Pan Ting,He Ran,Kong Feizhi,Cao Zhenmin,Ju Feiye,Huang Zhao,Nie Libo
Abstract
Microfluidic chip technology is a technology platform that integrates basic operation units such as processing, separation, reaction and detection into microchannel chip to realize low consumption, fast and efficient analysis of samples. It has the characteristics of small volume need of samples and reagents, fast analysis, low cost, automation, portability, high throughout, and good compatibility with other techniques. In this review, the concept, preparation materials and fabrication technology of microfluidic chip are described. The applications of microfluidic chip in immunoassay, including fluorescent, chemiluminescent, surface-enhanced Raman spectroscopy (SERS), and electrochemical immunoassay are reviewed. Look into the future, the development of microfluidic chips lies in point-of-care testing and high throughput equipment, and there are still some challenges in the design and the integration of microfluidic chips, as well as the analysis of actual sample by microfluidic chips.
Funder
Natural Science Foundation of Hunan Province
Scientific Research Foundation of Hunan Provincial Education Department
Subject
Biomedical Engineering,Histology,Bioengineering,Biotechnology
Cited by
12 articles.
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