Author:
Guo Xiujuan,Tian Hao,Yang Fan,Fan Sufang,Zhang Jingwen,Ma Junmei,Ai Lianfeng,Zhang Yan
Abstract
A multi-residue method has been developed for the identification and quantification of 103 common veterinary drug residues in milk and dairy Products. This method was based on QuEChERS with dispersive solid-phase where C18 sorbent and anhydrous sodium sulfate were used to sample purification. After evaporation and reconstitution, the samples were analyzed by ultra-performance liquid chromatography-tandem mass spectrometry. The mean recovery results were all higher than 60% except ampicillin, pipemidic acid, enoxacin, and estriol, and the relative standard deviation was <20.0%. The limit of quantification ranged between 0.1 and 5 μg/kg for milk and between 0.5 and 25 μg/kg for milk powder. It was successfully used to detect residues of veterinary drug in real samples. This study proposes a simple and fast analytical method for monitoring multi-class veterinary drug residues to ensure food safety.
Funder
Hebei Provincial Department of Bureau of Science and Technology
General Administration of Customs
Subject
Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Food Science
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