Pharmacodynamic Biomarkers for Emerging LRRK2 Therapeutics
Author:
Funder
National Institute of Neurological Disorders and Stroke
Publisher
Frontiers Media SA
Subject
General Neuroscience
Reference90 articles.
1. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.;Alegre-Abarrategui;Hum. Mol. Genet.,2009
2. A prototypical process for creating evidentiary standards for biomarkers and diagnostics.;Altar;Clin. Pharmacol. Ther.,2008
3. Biomarker qualification: toward a multiple stakeholder framework for biomarker development, regulatory acceptance, and utilization.;Amur;Clin. Pharmacol. Ther.,2015
4. PFE-360-induced LRRK2 inhibition induces reversible, non-adverse renal changes in rats.;Andersen;Toxicology,2018
5. Increased plasma neurofilament light chain concentration correlates with severity of post-mortem neurofibrillary tangle pathology and neurodegeneration.;Ashton;Acta Neuropathol. Commun.,2019
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