The Progress in the Application of Dissolving Microneedles in Biomedicine

Author:

Yu Xueqing123,Zhao Jing123,Fan Daidi123

Affiliation:

1. Engineering Research Center of Western Resource Innovation Medicine Green Manufacturing, Ministry of Education, School of Chemical Engineering, Northwest University, Xi’an 710069, China

2. Shaanxi Key Laboratory of Degradable Biomedical Materials and Shaanxi R&D Center of Biomaterials and Fermentation Engineering, School of Chemical Engineering, Northwest University, Xi’an 710069, China

3. Biotech & Biomed Research Institute, Northwest University, Xi’an 710069, China

Abstract

In recent years, microneedle technology has been widely used for the transdermal delivery of substances, showing improvements in drug delivery effects with the advantages of minimally invasive, painless, and convenient operation. With the development of nano- and electrochemical technology, different types of microneedles are increasingly being used in other biomedical fields. Recent research progress shows that dissolving microneedles have achieved remarkable results in the fields of dermatological treatment, disease diagnosis and monitoring, and vaccine delivery, and they have a wide range of application prospects in various biomedical fields, showing their great potential as a form of clinical treatment. This review mainly focuses on dissolving microneedles, summarizing the latest research progress in various biomedical fields, providing inspiration for the subsequent intelligent and commercial development of dissolving microneedles, and providing better solutions for clinical treatment.

Funder

National Key R&D Program of China

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Publisher

MDPI AG

Subject

Polymers and Plastics,General Chemistry

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