“Multiple Mode Procedures” of Ultra-Pulse Fractional CO2 Laser: A Novel Treatment Modality of Facial Atrophic Acne Scars

Author:

Pan Zhonglan1,Tang Yanqiu2,Hua Hui3,Hou Zuoqiong4,Zhou Bingrong2ORCID

Affiliation:

1. Nanjing Yijia Medical Aesthetic Clinic, Nanjing 210029, China

2. Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

3. Department of Dermatology, Nantong Third People’s Hospital Affiliated to Nantong University, Nantong 226000, China

4. Department of Burn and Plastic Surgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

Abstract

Background and aim: Fractional CO2 laser is therapeutic for acne atrophic scar, but its effect usually is limited after multiple sessions, with occasional adverse reactions. This study aimed to evaluate the efficacy and safety of a new modality combining ultra-pulse CO2 laser and fractional CO2 laser (multiple mode procedures [MMP]) in the treatment of acne atrophic scars. Method: From December 2017 to January 2023, a total of 103 patients with facial acne atrophic scars treated with MMP technique were retrospectively analyzed. MMP was performed for 1–4 sessions with an interval of approximately three months. Based on photographs taken before and after treatment, overall atrophic scar improvement was assessed according to the ECCA grading scale, the modified Manchester Scar Scale and the 4-point Global Assessment Scale (GAS). The safety was evaluated by the degree of pain during treatment and postoperative adverse reactions. Results: All the 103 patients received treatment and completed follow-up, with an average of two sessions. The mean ECCA score decreased from 162.7 to 93.1 with statistically significant difference (p < 0.001). The mean GAS score increased by an average of 2.3 ± 0.9. The GAS improvement more evident for “boxcar” atrophic scars (2.7 ± 0.8) than for “rolling” (2.3 ± 0.8) and “icepick” scars (1.7 ± 0.8) (p < 0.001). The average improvement scores for color, distortion and texture were 2.0 ± 0.9, 2.2 ± 0.9 and 2.3 ± 0.8, respectively. The mean pain score during treatment was 3.9 ± 0.8, and the mean duration of erythema was 30.7 ± 3.5 days. Only three patients developed hyperpigmentation at the treated site within a few months. Discussion: Ultra-pulse CO2 fractional laser MMP technique can effectively improve the condition of facial atrophic acne scars with limited adverse reactions.

Funder

China National Natural Science Foundation

Priority Academic Program Development (PAPD) of Jiangsu Higher Education Institutions

Outstanding Young and Middle-Aged Talents Support Program of the First Affiliated Hospital of Nanjing Medical University

Publisher

MDPI AG

Subject

General Medicine

Reference30 articles.

1. The epidemiology of acne vulgaris in late adolescence;Lynn;Adolesc. Health Med. Ther.,2016

2. Practical management of acne for clinicians: An international consensus from the Global Alliance to Improve Outcomes in Acne;Thiboutot;J. Am. Acad. Dermatol.,2018

3. Frequency and characteristics of acne-related post-inflammatory hyperpigmentation;Chow;J. Dermatol.,2016

4. Acne Scarring-Pathogenesis, Evaluation, and Treatment Options;Connolly;J. Clin. Aesthetic Dermatol.,2017

5. Acne Scars: How Do We Grade Them?;Clark;Am. J. Clin. Dermatol.,2018

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3