Treatment of erythematous acne scars using 595‐nm pulsed dye laser combined with 1565‐nm ResurFX nonablative fractional laser

Author:

Zhou Chenxi1,Yao Meijuan2,Chen Weiliang1,Zhang Liyuan1,Zhang Lidan2,Chen Mengjiao2,Li Kai1,Qin Xiaolei23

Affiliation:

1. DEXI Clinc, DE YI Skin Xi'An Shanxi China

2. DEYUE Clinc, DE YI Skin Shenzhen China

3. Peking University Shenzhen Hospital Shenzhen China

Abstract

AbstractBackgroundAcne vulgaris is a common inflammatory disease associated with various sequelae after skin lesion remission. Acne erythema has been considered simple erythema or a vascular lesion; however, because the understanding of this disease has improved, acne erythema is currently considered an early scar with erythematous components.AimsThis study evaluated the efficacy of using both a 595‐nm pulsed dye laser (PDL) and 1565‐nm nonablative fractional laser (NAFL) for the treatment of erythematous scars caused by acne.MethodsNinety patients with acne scars were equally randomized to two groups. Group A (n = 45) received treatment with the NAFL. Group B (n = 45) received treatment with the PDL and NAFL. Each patient underwent one treatment session and 4 weeks of follow‐up.ResultsQualitative (χ2 = 12.415; p < 0.05) and quantitative (t = 2.675; p < 0.05) scores of Groups A and B were determined using a global scarring grading system and exhibited statistically significant differences. The quantitative score of Group A was higher than that of Group B (6.67 ± 3.46 vs. 4.98 ± 2.44). The erythema areas of the groups differed significantly after treatment, with Group B exhibiting more notable score improvements (5.00 [3.10, 7.10] vs. 2.80 [1.65, 4.60]; Z = 3.072; p < 0.05). The erythema regression rate of Group B (88.9%) was significantly higher than that of Group A (66.7%) (χ2 = 20.295; p < 0.001). Adverse events, including redness and swelling (86.6%), scabbing (78.8%), and purpura (36.6%), occurred within 7 days for 86.6% of patients.ConclusionsThe combined use of the PDL and NAFL is safe and effective for erythematous acne scars.

Publisher

Wiley

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