Oxygenated Polyketides from Plakinastrella mamillaris as a New Chemotype of PXR Agonists-Reference-Cited by-同舟云学术

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Oxygenated Polyketides from Plakinastrella mamillaris as a New Chemotype of PXR Agonists

Published:2013-07-02 Issue:7 Volume:11 Page:2314-2327
ISSN:1660-3397
Container-title:Marine Drugs
language:en
Short-container-title:Marine Drugs

Author:

Festa Carmen,D'Amore Claudio,Renga Barbara,Lauro Gianluigi,Marino Simona,D'Auria Maria,Bifulco Giuseppe,Zampella Angela,Fiorucci Stefano

Publisher

MDPI AG

Subject

Drug Discovery,Pharmacology, Toxicology and Pharmaceutics (miscellaneous),Pharmaceutical Science

Link

http://www.mdpi.com/1660-3397/11/7/2314/pdf

Reference30 articles.

1. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

2. The Nuclear Pregnane X Receptor: A Key Regulator of Xenobiotic Metabolism

3. Evolution and Function of the NR1I Nuclear Hormone Receptor Subfamily (VDR, PXR, and CAR) with Respect to Metabolism of Xenobiotics and Endogenous Compounds

4. Dual role of orphan nuclear receptor pregnane X receptor in bilirubin detoxification in mice

5. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids

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