Evaluating Processing Speed and Reaction Time Outcome Measures in Children and Adolescents with Down Syndrome-Reference-Cited by-同舟云学术

Evaluating Processing Speed and Reaction Time Outcome Measures in Children and Adolescents with Down Syndrome

Published:2023-03-15 Issue:6 Volume:20 Page:5202
ISSN:1660-4601
Container-title:International Journal of Environmental Research and Public Health
language:en
Short-container-title:IJERPH

Author:

Schworer Emily K.¹²^ORCID,Altaye Mekibib³⁴,Fidler Deborah J.⁵^ORCID,Beebe Dean W.³⁶,Wiley Susan¹³,Hoffman Emily K.¹,Esbensen Anna J.¹³^ORCID

Affiliation:

1. Division of Developmental and Behavioral Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA

2. Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA

3. Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA

4. Division of Biostatistics and Epidemiology, Cincinnati Children’s Hospital, Cincinnati, OH 45229, USA

5. Human Development and Family Studies, Colorado State University, Fort Collins, CO 80523, USA

6. Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA

Abstract

Reliable and valid cognitive outcome measures, including examiner-administered and computer-facilitated assessments of processing speed and reaction time, are necessary for future clinical trials that include individuals with Down syndrome (DS). The current study evaluated the score distributions and psychometric properties of four examiner-administered and three computerized processing speed and reaction time measures. Participants included 97 individuals with DS, aged 6 to 17 (M = 12.6, SD = 3.3). Two examiner-administered measures (Differential Ability Scales-II Rapid Naming and Cat/dog Stroop Congruent) met most predetermined psychometric criteria. Other assessments demonstrated good test-retest reliability and had negligible practice effects but lacked adequate feasibility. Recommendations for using processing speed and reaction time assessments in research and suggestions for modifications of measures are discussed.

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

MDPI AG

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Link

https://www.mdpi.com/1660-4601/20/6/5202/pdf

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