Abstract
Complex and chronic wounds represent a highly prevalent condition worldwide that requires a multimodal and interdisciplinary treatment approach to achieve good functional and aesthetic outcomes. Due to increasing costs of health care, an aging population and an increase in difficult-to-treat microbial colonization of wounds, complex wounds will become a substantial clinical, social and economic challenge in the upcoming years. In plastic reconstructive surgery, a variety of dermal skin substitutes have been established for clinical use. Since its approval as a dermal skin substitute in Germany, NovoSorb® Biodegradable Temporising Matrix (BTM) has become a valuable therapeutic option for the treatment of full-thickness wound defects. The clinical data published to date are limited to case reports and small-scale case series with the main focus on single wounds. The aim of this single-center study was a retrospective analysis of our own patient collective that has received treatment with BTM for complex wounds. Overall, BTM showed to be a reliable and versatile reconstructive option, especially for patients with multiple co-morbidities and microbiologically colonized wounds. Although the preliminary findings have produced promising results, further investigation and research are warranted regarding long-term outcomes and additional clinical applications.
Reference47 articles.
1. Nguyen, A.V., and Soulika, A.M. (2019). The Dynamics of the Skin’s Immune System. Int. J. Mol. Sci., 20.
2. Welsch, U. (2006). Sobotta Lehrbuch Histologie: Zytologie, Histologie, Mikroskopische Anatomie, Urban & Fischer Verlag/Elsevier GmbH.
3. Complex Wounds and Their Management;Park;Surg. Clin. N. Am.,2010
4. Complex wounds;Ferreira;Clinics,2006
5. Science, medicine, and the future: Healing chronic wounds;Harding;BMJ,2002
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