Affiliation:
1. College of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, China
2. School of Materials and Energy, Guangdong University of Technology, Guangzhou 510030, China
Abstract
The treatment of skin wounds caused by trauma and pathophysiological disorders has been a growing healthcare challenge, posing a great economic burden worldwide. The use of appropriate wound dressings can help to facilitate the repair and healing rate of defective skin. Natural polymer biomaterials such as collagen and hyaluronic acid with excellent biocompatibility have been shown to promote wound healing and the restoration of skin. However, the low mechanical properties and fast degradation rate have limited their applications. Skin wound dressings based on biodegradable and biocompatible synthetic polymers can not only overcome the shortcomings of natural polymer biomaterials but also possess favorable properties for applications in the treatment of skin wounds. Herein, we listed several biodegradable and biocompatible synthetic polymers used as wound dressing materials, such as PVA, PCL, PLA, PLGA, PU, and PEO/PEG, focusing on their composition, fabrication techniques, and functions promoting wound healing. Additionally, the future development prospects of synthetic biodegradable polymer-based wound dressings are put forward. Our review aims to provide new insights for the further development of wound dressings using synthetic biodegradable polymers.
Funder
Zhejiang Provincial Natural Science Foundation of China
Research Project on Chinese Medicine Health Services
College level scientific research cultivation project of Zhejiang Chinese Medical University
Research Project of Zhejiang Chinese Medical University
Program of Xinmiao Potential Talents in Zhejiang Province
Subject
General Materials Science
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