Affiliation:
1. College of Food Science, Sichuan Agricultural University, Ya’an 625014, China
2. College of Resources, Sichuan Agricultural University, Chengdu 611130, China
Abstract
Norfloxacin (NOR) is a common antibiotic used in humans and animals, and its high levels can cause intolerance or poisoning. Therefore, NOR levels in animal-derived foods must be monitored due to potential side effects and illegal use phenomena. This research centered on the development of an environmentally friendly electrochemical sensor for NOR detection. Potassium carbonate activated tea branch biochar (K-TBC) as an efficient use of waste was coated on the surface of glassy carbon electrode (GCE), and a molecular-imprinted polymer (MIP) layer was subsequently electropolymerized onto the modified electrode. NOR was used as template molecule and o-phenylenediamine (o-PD) and o-aminophenol (o-AP) were used as bifunctional monomers. The electrochemical sensor was built and its electrochemical behavior on NOR was investigated. The sensor demonstrated an excellent linear current response to NOR concentrations in the ranges of 0.1–0.5 nM and 0.5–100 nM under ideal experimental circumstances, with a detection limit of 0.028 nM (S/N = 3). With recoveries ranging from 85.90% to 101.71%, the designed sensor was effectively used to detect NOR in actual samples of milk, honey, and pork. Besides, the fabricated sensor had low price, short detection time, good selectivity and stability, which can provide a theoretical and practical basis for the actual monitoring of NOR residues.
Funder
Department of Science and Technology of Sichuan Province
Project Technology Innovation Research and Development of Chengdu Science and Technology Bureau
Subject
Plant Science,Health Professions (miscellaneous),Health (social science),Microbiology,Food Science
Reference50 articles.
1. Antibacterial activity of norfloxacin;Norrby;Antimicrob. Agents Chemother.,1983
2. Review of Properties and Analytical Methods for the Determination of Norfloxacin;Lucas;Crit. Rev. Anal. Chem.,2015
3. Oral Fluoroquinolones;Califf;J. Am. Coll. Cardiol.,2019
4. Fluoroquinolones are associated with increased risk of aortic aneurysm or dissection: Systematic review and meta-analysis;Ribeiro;Semin. Thorac. Cardiovasc. Surg.,2021
5. Occurrence, distribution, and health risk assessmentof quinolone antibiotics in watcr, sediment, and fish species of Qingshitan reservoir, South China;Huang;Sci. Rep.,2020
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