High Mitochondrial Haplotype Diversity Found in Three Pre-Hispanic Groups from Colombia

Author:

Uricoechea Patiño Daniel1,Collins Andrew2ORCID,García Oscar Julián Romero3,Santos Vecino Gustavo4,Cuenca José Vicente Rodríguez5,Bernal Jaime E.6,Benavides Benítez Escilda6,Vergara Muñoz Saray6,Briceño Balcázar Ignacio1

Affiliation:

1. Doctoral Program in Biosciences, Human Genetics Group, Faculty of Medicine, University of La Sabana, Chía 250001, Colombia

2. Human Genetics & Genomic Medicine, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK

3. Genetics Group, National Institute of Legal Medicine and Forensic Sciences, Bogotá 110311, Colombia

4. Department of Anthropology, Faculty of Social and Human Science, Universidad de Antioquia, Medellín 050010, Colombia

5. Research Group in Biological Anthropology, Universidad Nacional de Colombia, Bogotá 111321, Colombia

6. Faculty of Medicine, University of Sinú, Cartagena de Indias 130011, Colombia

Abstract

The analysis of mitochondrial DNA (mtDNA) hypervariable region (HVR) sequence data from ancient human remains provides valuable insights into the genetic structure and population dynamics of ancient populations. mtDNA is particularly useful in studying ancient populations, because it is maternally inherited and has a higher mutation rate compared to nuclear DNA. To determine the genetic structure of three Colombian pre-Hispanic populations and compare them with current populations, we determined the haplotypes from human bone remains by sequencing several mitochondrial DNA segments. A wide variety of mitochondrial polymorphisms were obtained from 33 samples. Our results support a high population heterogeneity among pre-Hispanic populations in Colombia.

Funder

Universidad de La Sabana

Publisher

MDPI AG

Subject

Genetics (clinical),Genetics

Reference86 articles.

1. Reichel-Dolmatoff, G. (1978). Manual de Historia de Colombia Tomo i, Instituto Colombiano de Cultura.

2. Langebaek, C.H. (2019). Los Muiscas. La Historia Milenaria de un Pueblo Chibcha, Debate.

3. Early prehispanic settlement in the Magdalena Valley in Tolima, Colombia. Balance and perspectives;Barbosa;Quat. Int.,2019

4. Pleistocene man in South America;Lanning;World Archaeol.,1970

5. Historical patterns and drivers of landscape change in Colombia since 1500: A regionalized spatial approach;Etter;Ann. Assoc. Am. Geogr.,2008

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3