Unraveling the Genetic Threads of History: mtDNA HVS-I Analysis Reveals the Ancient Past of the Aburra Valley

Author:

Uricoechea Patiño Daniel1,Collins Andrew2ORCID,Romero García Oscar Julián3,Santos Vecino Gustavo4,Aristizábal Espinosa Pablo5,Bernal Villegas Jaime Eduardo6,Benavides Benitez Escilda6,Vergara Muñoz Saray6,Briceño Balcázar Ignacio1

Affiliation:

1. Doctoral Program in Biosciences, Human Genetics Group, Faculty of Medicine, University of La Sabana, Chía 250001, Colombia

2. Human Genetics & Genomic Medicine, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK

3. Genetics Group, National Institute of Legal Medicine and Forensic Sciences, Bogotá 110311, Colombia

4. Department of Anthropology, Faculty of Social and Human Science, Universidad de Antioquia, Medellín 050010, Colombia

5. School for Advanced Studies in the Social Sciences, Americanists Society of Paris, 75006 Paris, France

6. Faculty of Medicine, University of Sinú, Cartagena de Indias 130011, Colombia

Abstract

This article presents a comprehensive genetic study focused on pre-Hispanic individuals who inhabited the Aburrá Valley in Antioquia, Colombia, between the tenth and seventeenth centuries AD. Employing a genetic approach, the study analyzed maternal lineages using DNA samples obtained from skeletal remains. The results illuminate a remarkable degree of biological diversity within these populations and provide insights into their genetic connections with other ancient and indigenous groups across the American continent. The findings strongly support the widely accepted hypothesis that the migration of the first American settlers occurred through Beringia, a land bridge connecting Siberia to North America during the last Ice Age. Subsequently, these early settlers journeyed southward, crossing the North American ice cap. Of particular note, the study unveils the presence of ancestral lineages from Asian populations, which played a pivotal role in populating the Americas. The implications of these results extend beyond delineating migratory routes and settlement patterns of ancient populations. They also enrich our understanding of the genetic diversity inherent in indigenous populations of the region. By revealing the genetic heritage of pre-Hispanic individuals from the Aburrá Valley, this study offers valuable insights into the history of human migration and settlement in the Americas. Furthermore, it enhances our comprehension of the intricate genetic tapestry that characterizes indigenous communities in the area.

Funder

Universidad de La Sabana

Publisher

MDPI AG

Subject

Genetics (clinical),Genetics

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