Bioactive Compounds for Combating Oxidative Stress in Dermatology

Author:

Turcov Delia12,Zbranca-Toporas Anca2ORCID,Suteu Daniela1

Affiliation:

1. Faculty of Chemical Engineering and Environmental Protection “Cristofor Simionescu”, “Gheorghe Asachi” Technical University, 71 A Mangeron Blvd., 700500 Iasi, Romania

2. Faculty of Medical Bioengineering, “Grigore T. Popa” University of Medicine and Pharmacy, Universitatii Street no. 16, 700115 Iasi, Romania

Abstract

There are extensive studies that confirm the harmful and strong influence of oxidative stress on the skin. The body’s response to oxidative stress can vary depending on the type of reactive oxygen species (ROS) or reactive nitrogen species (RNS) and their metabolites, the duration of exposure to oxidative stress and the antioxidant capacity at each tissue level. Numerous skin diseases and pathologies are associated with the excessive production and accumulation of free radicals. title altered Both categories have advantages and disadvantages in terms of skin structures, tolerability, therapeutic performance, ease of application or formulation and economic efficiency. The effect of long-term treatment with antioxidants is evaluated through studies investigating their protective effect and the improvement of some phenomena caused by oxidative stress. This article summarizes the available information on the presence of compounds used in dermatology to combat oxidative stress in the skin. It aims to provide an overview of all the considerations for choosing an antioxidant agent, the topics for further research and the answers sought in order to optimize therapeutic performance.

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

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