Regenerative Cosmetics: Skin Tissue Engineering for Anti-Aging, Repair, and Hair Restoration

Author:

Pleguezuelos-Beltrán Paula1234ORCID,Herráiz-Gil Sara5678,Martínez-Moreno Daniel1234,Medraño-Fernandez Iria9,León Carlos5678ORCID,Guerrero-Aspizua Sara5678ORCID

Affiliation:

1. BioFab i3D Lab-Biofabrication and 3D (Bio)printing Laboratory, Department of Human Anatomy and Embryology, Faculty of Medicine, University of Granada, 18016 Granada, Spain

2. Excellence Research Unit “Modeling Nature” (MNat), University of Granada, 18016 Granada, Spain

3. Instituto de Investigación Biosanitaria ibs.GRANADA, University of Granada, 18016 Granada, Spain

4. Biopathology and Regenerative Medicine Institute (IBIMER), Center for Biomedical Research (CIBM), University of Granada, 18016 Granada, Spain

5. Department of Bioengineering, Carlos III University, UC3M-IISFJD-CIEMAT-CIBERER, Av. de la Universidad 30, Leganés, 28911 Madrid, Spain

6. Network Research on Rare Diseases (CIBERER), U714, C/Melchor Fernández Almagro, 3, 28029 Madrid, Spain

7. Health Research Institute-Jiménez Díaz Foundation University Hospital (IIS-FJD), Av. de los Reyes Católicos, 2, 28040 Madrid, Spain

8. Centre for Energy, Environment and Technology Research (CIEMAT), Av. Complutense 40, 28040 Madrid, Spain

9. Department of Neurosciences and Biomedical Sciences, Faculty of Health Sciences, Carlos III University, Calle Madrid 126, Getafe, 28903 Madrid, Spain

Abstract

The quest for youthful, healthy skin and full, vibrant hair has long been a driving force in the dermocosmetics field. However, traditional approaches often struggle to address the underlying causes of aging, damage, and hair loss. Regenerative cosmetics powered by skin tissue engineering offer a transformative alternative. This review explores the emerging field of using engineered skin tissues for cosmetic purposes, focusing specifically on their potential for anti-aging, repair, and hair restoration applications. We discuss how these technologies aim to rejuvenate aging skin by promoting collagen production, reducing wrinkles, and improving overall skin function. Additionally, the use of engineered skin for wound healing and scar reduction is examined, highlighting their potential to improve the appearance and functionality of damaged skin. Finally, we advance the exciting prospects of utilizing skin tissue engineering techniques to regenerate hair follicles, potentially offering solutions for hair loss and promoting denser hair growth.

Funder

Spanish Ministry of Science and Innovation and the European Regional Development fund

Institute of Health Carlos III

UC3M–PhD research training scholarship

Madrid Government

“Proyectos de I + D + I”

HORIZON-CHIPS-JU-2021-2-RIA

Ministerio de Ciencia e Innovación

Publisher

MDPI AG

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