Geometrical Characterisation of TiO2-rGO Field-Effect Transistor as a Platform for Biosensing Applications

Author:

Alim Anis Amirah1,Roslan Roharsyafinaz1,Nadzirah Sh.12,Saidi Lina Khalida3,Menon P. Susthitha1ORCID,Aziah Ismail4ORCID,Chang Fu Dee1ORCID,Sulaiman Siti Aishah3ORCID,Abdul Murad Nor Azian3,Hamzah Azrul Azlan1ORCID

Affiliation:

1. Institute of Microengineering and Nanoelectronics, National University of Malaysia, Bangi 43600, Selangor, Malaysia

2. Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, Kangar 01000, Perlis, Malaysia

3. UKM Medical Molecular Biology Institute (UMBI), National University of Malaysia, Cheras 56000, Kuala Lumpur, Malaysia

4. Institute for Research in Molecular Medicine (INFORMM), Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia

Abstract

The performance of the graphene-based field-effect transistor (FET) as a biosensor is based on the output drain current (Id). In this work, the signal-to-noise ratio (SNR) was investigated to obtain a high-performance device that produces a higher Id value. Using the finite element method, a novel top-gate FET was developed in a three-dimensional (3D) simulation model with the titanium dioxide-reduced graphene oxide (TiO2-rGO) nanocomposite as the transducer material, which acts as a platform for biosensing application. Using the Taguchi mixed-level method in Minitab software (Version 16.1.1), eighteen 3D models were designed based on an orthogonal array L18 (6134), with five factors, and three and six levels. The parameters considered were the channel length, electrode length, electrode width, electrode thickness and electrode type. The device was fabricated using the conventional photolithography patterning technique and the metal lift-off method. The material was synthesised using the modified sol–gel method and spin-coated on top of the device. According to the results of the ANOVA, the channel length contributed the most, with 63.11%, indicating that it was the most significant factor in producing a higher Id value. The optimum condition for the highest Id value was at a channel length of 3 µm and an electrode size of 3 µm × 20 µm, with a thickness of 50 nm for the Ag electrode. The electrical measurement in both the simulation and experiment under optimal conditions showed a similar trend, and the difference between the curves was calculated to be 28.7%. Raman analyses were performed to validate the quality of TiO2-rGO.

Funder

Geran Universiti Penyelidikan

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering

Reference43 articles.

1. Progress in utilisation of graphene for electrochemical biosensors;Lawal;TrAC Trends Anal. Chem.,2017

2. Titanium dioxide–mediated resistive nanobiosensor for E. coli O157:H7;Nadzirah;Microchim. Acta,2020

3. Yazeer, M.J., Za’Bah, N.F., and Alam, A.H.M.Z. (2016, January 26–27). Triangular Shaped Silicon Nanowire FET Characterization Using COMSOL Multiphysics. Proceedings of the 6th International Conference on Computer and Communication Engineering: Innovative Technologies to Serve Humanity, ICCCE, Kuala Lumpur, Malaysia.

4. Carbon nanodots based biosensors for gene mutation detection;Bravo;Sens. Actuators B Chem.,2018

5. Fabrication of graphene-based back-gated field effect transistor for cortisol detection;Maidin;Int. J. Nanoelectron. Mater.,2018

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