The Genus Miconia Ruiz & Pav. (Melastomataceae): Ethnomedicinal Uses, Pharmacology, and Phytochemistry

Author:

da Silva Viviane BezerraORCID,Almeida-Bezerra José WevertonORCID,Costa Adrielle Rodrigues,Morais-Braga Maria Flaviana BezerraORCID,de Oliveira Maraiza Gregorio,Pinheiro Anderson Angel VieiraORCID,Sampaio Raimundo Samuel Leite,Castro José Walber Gonçalves,dos Santos Marcos Aurélio Figueiredo,Ulisses Valdilia Ribeiro de Alencar,Pereira Maria Edilania da Silva Serafim,Souza Dieferson Leandro deORCID,Alcântara Bruno Melo de,Generino Maria Elizete Machado,Silva José Thyálisson da Costa,Filho Ademar MaiaORCID,Silva Sabrina Bezerra da,Moon Myunghan,Kim BongleeORCID,Costa José Galberto Martins da

Abstract

Species of the genus Miconia are used in traditional medicine for the treatment of diseases, such as pain, throat infections, fever, and cold, and they used as depuratives, diuretics, and sedatives. This work reviewed studies carried out with Miconia species, highlighting its ethnomedicinal uses and pharmacological and phytochemical potential. This information was collected in the main platforms of scientific research (PubMed, Scopus, and Web of Science). Our findings show that some of the traditional uses of Miconia are corroborated by biological and/or pharmacological assays, which demonstrated, among other properties, anti-inflammatory, analgesic, antimutagenic, antiparasitic, antioxidant, cytotoxic, and antimicrobial activities. A total of 148 chemical compounds were identified in Miconia species, with phenolic compounds being the main constituents found in the species of this genus. Such phytochemical investigations have demonstrated the potential of species belonging to this genus as a source of bioactive substances, thus reinforcing their medicinal and pharmacological importance.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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