Sintered and 3D-Printed Bulks of MgB2-Based Materials with Antimicrobial Properties

Author:

Badica PetreORCID,Batalu Nicolae DanORCID,Chifiriuc Mariana CarmenORCID,Burdusel Mihail,Grigoroscuta Mihai Alexandru,Aldica Gheorghe Virgil,Pasuk IulianaORCID,Kuncser Andrei,Popa MarcelaORCID,Agostino AngeloORCID,Operti LorenzaORCID,Padhi Santanu KumarORCID,Bonino Valentina,Truccato MarcoORCID

Abstract

Pristine high-density bulk disks of MgB2 with added hexagonal BN (10 wt.%) were prepared using spark plasma sintering. The BN-added samples are machinable by chipping them into desired geometries. Complex shapes of different sizes can also be obtained by the 3D printing of polylactic acid filaments embedded with MgB2 powder particles (10 wt.%). Our present work aims to assess antimicrobial activity quantified as viable cells (CFU/mL) vs. time of sintered and 3D-printed materials. In vitro antimicrobial tests were performed against the bacterial strains Escherichia coli ATCC 25922, Pseudomonas aeruginosa ATCC 27853, Staphylococcus aureus ATCC 25923, Enterococcus faecium DSM 13590, and Enterococcus faecalis ATCC 29212; and the yeast strain Candida parapsilosis ATCC 22019. The antimicrobial effects were found to depend on the tested samples and microbes, with E. faecium being the most resistant and E. coli the most susceptible.

Funder

Romanian National Authority for Scientific Research and Innovation

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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