Author:
Zhang Sha,Chen Dekun,Kuang Min,Peng Weiwei,Chen Yan,Tan Jianbing,Kang Fenghua,Xu Kangping,Zou Zhenxing
Abstract
Two new phthalide derivatives, rhytidhylides A (1) and B (2), together with ten known compounds (3–12) were isolated from cultures of Rhytidhysteron sp. BZM-9, an endophyte isolated from the leaves of Leptospermum brachyandrum. Their structures were identified by an extensive analysis of NMR, HRESIMS, ECD, and through comparison with data reported in the literature. In addition, the cytotoxic activities against two human hepatoma cell lines (HepG2 and SMMC7721) and antibacterial activities against MRSA and E. coli were evaluated.
Funder
Natural Science Foundation of Hunan Province
Science and Technology Program of Hunan Province
Postgraduates Innovation Program of Central South University
Subject
Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science
Cited by
11 articles.
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