Natural Products and Biological Activity from Actinomycetes Associated with Marine Algae

Author:

Xiong Zijun1ORCID,Wang Rong2,Xia Tengfei3ORCID,Zhang Shiqing1,Ma Shuai1,Guo Zhikai1

Affiliation:

1. Hainan Key Laboratory of Tropical Microbe Resources, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences & Key Laboratory for Biology and Genetic Resources of Tropical Crops of Hainan Province, Hainan Institute for Tropical Agricultural Resources, Haikou 571101, China

2. Hainan Provincial Key Laboratory of Tropical Maricultural Technologies, Hainan Academy of Ocean and Fisheries Sciences, Haikou 571126, China

3. Institute of Tropical Horticulture Research, Hainan Academy of Agricultural Sciences, Haikou 571100, China

Abstract

Marine natural products have been recognized as the most promising source of bioactive substances for drug discovery research. This review illustrates the diversity of culturable actinobacteria associated with marine algae, their bioactivity and metabolites, and approaches to their isolation and determination of their biological properties. Furthermore, actinobacteria associated with marine algae are presented as a new subject for an extensive investigation to find novel and active natural products, which make them a potentially rich and innovative source for new drug development deserving more attention and exploration.

Funder

Key Research Program of Hainan Province

Natural Science Foundation of Hainan

Financial Fund of the Ministry of Agriculture and Rural Affairs, P. R. of China

Central Public-interest Scientific Institution Basal Research Fund for CATAS-ITBB

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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