Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents-Reference-Cited by-同舟云学术

Facile Synthesis of a Series of Non-Symmetric Thioethers Including a Benzothiazole Moiety and Their Use as Efficient In Vitro anti-Trypanosoma cruzi Agents

Published:2019-08-24 Issue:17 Volume:24 Page:3077
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Avila-Sorrosa Alcives^ORCID,Tapia-Alvarado Jazz D.,Nogueda-Torres Benjamín,Chacón-Vargas Karla Fabiola,Díaz-Cedillo Francisco,Vargas-Díaz María Elena,Morales-Morales David^ORCID

Abstract

A series of 2-benzylsulfanyl benzothiazole (BTA) derivatives were synthesized and fully characterized and in vitro tested against two strains of T. cruzi (NINOA and INC-5), exhibiting good activities at low concentrations.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/24/17/3077/pdf

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3. Benzothiazoles: Search for anticancer agents

4. 1,2,4-Triazole-based benzothiazole/benzoxazole derivatives: Design, synthesis, p38α MAP kinase inhibition, anti-inflammatory activity and molecular docking studies

5. Antimalarials. III. Benzothiazole amino alcohols

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