Enantioselective Synthesis of a New Non-Natural Gabosine-Reference-Cited by-同舟云学术

Enantioselective Synthesis of a New Non-Natural Gabosine

Published:2021-03-06 Issue:5 Volume:26 Page:1423
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Colobbio Maximiliano,Pandolfi Enrique,Schapiro Valeria

Abstract

The preparation of a new non-natural gabosine is reported, in which the chirality is transferred from the toluene’s biotransformed metabolite (1R,2S)-3-methylcyclohexa-3.5-diene-1,2-diol. Further chemical transformations to introduce additional functionality and chirality to the molecule were also accomplished.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/26/5/1423/pdf

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