Anthocyanins: Potential Therapeutic Approaches towards Obesity and Diabetes Mellitus Type 2

Author:

Franco-San Sebastián Denise1,Alaniz-Monreal Samary1ORCID,Rabadán-Chávez Griselda2,Vázquez-Manjarrez Natalia3,Hernández-Ortega Marcela1,Gutiérrez-Salmeán Gabriela1ORCID

Affiliation:

1. Centro de Investigación en Ciencias de la Salud (CICSA), Facultad de Ciencias de la Salud, Universidad Anáhuac México, Huixquilucan 52786, Mexico

2. Instituto para la Investigación en Obesidad, Instituto Tecnológico y de Estudios Superiores de Monterrey, Campus Guadalajara, Guadalajara 64849, Mexico

3. Unidad de Metabolómica, Dirección de Nutrición, Instituto de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de Mexico 14080, Mexico

Abstract

Overweight and obesity are present in about three-quarters of the adult population in Mexico. The inflammatory mechanisms subjacent to visceral white adipose tissue are accountable for the initiation and development of cardiometabolic alterations, including type 2 diabetes. Lifestyle changes are pillars within its therapeutics and, thus, current dietary modifications should include not only hypocaloric prescriptions with balanced macronutrient intake, preferably by increasing the amount of whole grains, fruits, vegetables, nuts and legumes, but in concomitance, bioactive substances, such as anthocyanins, have been correlated with lower incidence of this disease.

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

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