1. Polytechnic University of Coimbra, Coimbra Health School, 3046-854 Coimbra, Portugal
2. Coimbra Institute for Clinical and Biomedical Research (iCBR) and Institute of Physiology, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal
3. Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3000-548 Coimbra, Portugal
4. Clinical Academic Center of Coimbra (CACC), 3000-548 Coimbra, Portugal