Current Evidence on Bisphenol A Exposure and the Molecular Mechanism Involved in Related Pathological Conditions-Reference-Cited by-同舟云学术

Current Evidence on Bisphenol A Exposure and the Molecular Mechanism Involved in Related Pathological Conditions

Published:2023-03-10 Issue:3 Volume:15 Page:908
ISSN:1999-4923
Container-title:Pharmaceutics
language:en
Short-container-title:Pharmaceutics

Author:

Della Rocca Ylenia¹,Traini Enrico Matteo¹,Diomede Francesca¹^ORCID,Fonticoli Luigia¹,Trubiani Oriana¹^ORCID,Paganelli Alessia²^ORCID,Pizzicannella Jacopo³,Marconi Guya Diletta¹^ORCID

Affiliation:

1. Department of Innovative Technologies in Medicine & Dentistry, University “G. d’Annunzio” Chieti-Pescara, Via dei Vestini 31, 66100 Chieti, Italy

2. PhD Course in Clinical and Experimental Medicine, University of Modena and Reggio Emilia, Via del Pozzo 71, 41125 Modena, Italy

3. Department of Engineering and Geology, University “G. d’ Annunzio” Chieti-Pescara, Viale Pindaro 42, 65127 Pescara, Italy

Abstract

Bisphenol A (BPA) is one of the so-called endocrine disrupting chemicals (EDCs) and is thought to be involved in the pathogenesis of different morbid conditions: immune-mediated disorders, type-2 diabetes mellitus, cardiovascular diseases, and cancer. The purpose of this review is to analyze the mechanism of action of bisphenol A, with a special focus on mesenchymal stromal/stem cells (MSCs) and adipogenesis. Its uses will be assessed in various fields: dental, orthopedic, and industrial. The different pathological or physiological conditions altered by BPA and the related molecular pathways will be taken into consideration.

Publisher

MDPI AG

Subject

Pharmaceutical Science

Link

https://www.mdpi.com/1999-4923/15/3/908/pdf

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