Bisphenol-A (BPA) Exposure as a Risk Factor for Non-Communicable Diseases

Abstract

Bisphenol-A (BPA) is a widely used chemical compound in the production of consumer items and building materials. Over the years, concerns have been raised about its potential adverse effects on human health. This chapter aims to explore the existing evidence regarding the association between BPA exposure and the risk of non-communicable diseases (NCDs). NCDs, such as cardiovascular diseases, diabetes, obesity, and certain types of cancer, are the leading causes of morbidity and mortality worldwide. Multiple studies have investigated the potential role of BPA in the development and progression of these diseases. Epidemiological studies have also provided evidence suggesting a link between BPA exposure and NCDs in humans. Several potential mechanisms have been proposed to explain the effects of BPA on NCDs, including its ability to mimic estrogenic activity and alter hormone signaling. A broader knowledge of the association between BPA and NCDs can inform public health policies and strategies aimed at reducing BPA exposure towards mitigating the burden of NCDs. In general, while the evidence regarding the association between BPA exposure and NCDs is still evolving, the existing literature suggests a potential link between BPA exposure and an increased risk of developing various non-communicable diseases.