Topical Probiotic Hydrogels for Burn Wound Healing

Author:

Arshad Tavinda1,Mundrathi Varsha1ORCID,Perez Victoria E.1,Nunez Jeilyn M.1,Cho Hyunah1

Affiliation:

1. Industrial Pharmacy, Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John’s University, Queens, NY 11439, USA

Abstract

Hydrogels have increasingly been used to enhance the effective healing of various wounds, including burn wounds. Similarly, the application of probiotics has recently been explored in wound healing and skin repairs. While probiotics have been consumed to provide therapeutic effects that aid with improving gut health, topical applications have been found to accelerate wound healing both in vitro and in vivo. For wounds that have complex healing mechanisms, such as burn wounds which depend on factors such as the depth of the burn, size of the afflicted area, and cause of the injury, probiotics with or without conventional therapeutic agents topically delivered via hydrogel technology are proven to be effective in the recovery of the damaged skin. This article aims to investigate the microorganisms present in the human skin microbiome and observe the effects of probiotics delivered by hydrogels on burn wound healing.

Publisher

MDPI AG

Reference57 articles.

1. Carmona-Cruz, S., Orozco-Covarrubias, L., and Sáez-de-Ocariz, M. (2022). The Human Skin Microbiome in Selected Cutaneous Diseases. Front. Cell. Infect. Microbiol., 12.

2. Antimicrobials from Human Skin Commensal Bacteria Protect against Staphylococcus aureus and Are Deficient in Atopic Dermatitis;Nakatsuji;Sci. Transl. Med.,2017

3. Highly Active Probiotic Hydrogels Matrixed on Bacterial EPS Accelerate Wound Healing via Maintaining Stable Skin Microbiota and Reducing Inflammation;Xu;Bioact. Mater.,2024

4. Injectable and Self-Healing Probiotics-Loaded Hydrogel for Promoting Superbacteria-Infected Wound Healing;Mei;ACS Appl. Mater. Interfaces,2022

5. The Human Skin Microbiome;Byrd;Nat. Rev. Microbiol.,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3