miRNAs: Targets to Investigate Herpesvirus Infection Associated with Neurological Disorders

Author:

de Souza Carneiro Vanessa Cristine12,Leon Luciane Almeida Amado2,de Paula Vanessa Salete1

Affiliation:

1. Laboratory of Molecular Virology and Parasitology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, Brazil

2. Laboratory of Technological Development in Virology, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro 21040-360, Brazil

Abstract

Herpesvirus is associated with various neurological disorders and a specific diagnosis is associated with a better prognosis. MicroRNAs (miRNAs) are potential diagnostic and prognostic biomarkers of neurological diseases triggered by herpetic infection. In this review, we discuss miRNAs that have been associated with neurological disorders related to the action of herpesviruses. Human miRNAs and herpesvirus-encoded miRNAs were listed and discussed. This review article will be valuable in stimulating the search for new diagnostic and prognosis alternatives and understanding the role of these miRNAs in neurological diseases triggered by herpesviruses.

Funder

Coordination for the Improvement of Higher Education Personnel

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

Oswaldo Cruz Institute

Conselho Nacional de Desenvolvimento Científico e Tecnológico

FAPERJ-JCNE

INOVA/Fiocruz-geração

Publisher

MDPI AG

Subject

Inorganic Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Computer Science Applications,Spectroscopy,Molecular Biology,General Medicine,Catalysis

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