Impact of a Primary Care Antimicrobial Stewardship Program on Bacterial Resistance Control and Ecological Imprint in Urinary Tract Infections
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Published:2022-12-08
Issue:12
Volume:11
Page:1776
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ISSN:2079-6382
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Container-title:Antibiotics
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language:en
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Short-container-title:Antibiotics
Author:
Jover-Sáenz AlfredoORCID, Ramírez-Hidalgo MaríaORCID, Bellés Bellés AlbaORCID, Ribes Murillo EstherORCID, Batlle Bosch Meritxell, Cayado Cabanillas José, Garrido-Calvo Sònia, Gracia Vilas María Isabel, Gros Navés Laura, Javierre Caudevilla María Jesús, Mari López Alba, Montull Navarro Lidia, Ortiz Valls Mireia, Terrer Manrique Gemma, Vaqué Castilla Pilar, Ichart Tomás José JavierORCID, Justribó Sánchez Elena, Andreu Mayor Ester, Carrera Guiu Joan, Martorell Solé Roser, Pallàs Satué Silvia, Saura Codina Mireia, Vena Martínez AnaORCID, Albalat Samper José Manuel, Cano Marrón Susana, Chacón Domínguez Isabel, Escuin David de la Rica, Estadella Servalls María José, Figueres Farreny Ana M., Minguet Vidal Sonia, Montaña Esteban Luís Miguel, Otal Bareche Josep, Pallerola Planes Mercè, Pujol Aymerich Francesc, Rodríguez Garrocho AndrésORCID, Solé Curcó Antoni, Toribio Redondo Francisca, Urgelés Castillón María CruzORCID, Valgañon Palacios Juan, Torres-Puig-gros JoanORCID, ,
Abstract
Antimicrobial stewardship programs (ASPs) are a central component in reducing the overprescription of unnecessary antibiotics, with multiple studies showing benefits in the reduction of bacterial resistance. Less commonly, ASPs have been performed in outpatient settings, but there is a lack of available data in these settings. We implemented an ASP in a large regional outpatient setting to assess its feasibility and effectiveness. Over a 5-year post-implementation period, compared to the pre-intervention period, a significant reduction in antibiotic prescription occurred, with a reduction in resistance in E. coli urinary isolates. ASP activities also were found to be cost-effective, with a reduction in medication prescription.
Subject
Pharmacology (medical),Infectious Diseases,Microbiology (medical),General Pharmacology, Toxicology and Pharmaceutics,Biochemistry,Microbiology
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