GenomeBits Characterization of MPXV

Author:

Canessa Enrique

Abstract

Genome sequences of the monkeypox virus (MPXV) causing the current outbreak are being reported from an increasing number of countries. We present a letter-to-numerical sequence study via GenomeBits signal mapping in order to characterize the evolution of the MPXV via simple statistical analysis. Histograms, empirical and theoretical cumulative distribution curves and the resulting scatter plots for the base nucleotides A and C versus their complementary base nucleotides T and G are discussed. GenomeBits may help the surveillance of emergent infectious diseases.

Publisher

MDPI AG

Subject

Genetics (clinical),Genetics

Reference14 articles.

1. WHO (2022, November 24). Disease Outbreak News. Multi-Country Monkeypox Outbreak in Non-Endemic Countries, Available online: https://www.who.int/emergencies/disease-outbreak-news/item/2022-DON385.

2. GISAID (2022, November 24). Global Science Initiative—Open Access Archive to Genomic Data of Viruses. Available online: http://www.gisaid.org.

3. GenBank (2022, November 24). NIH Genetic Sequence Database—An Annotated Collection of All Publicly Available DNA Sequences, Available online: https://www.ncbi.nlm.nih.gov/genbank/.

4. Multiple lineages of monkeypox virus detected in the United States, 2021–2022;Gigante;Science,2022

5. Falendysz, E.A., Lopera, J.G., Doty, J.B., Nakazawa, Y., Crill, C., Lorenzsonn, F., Kalemba, L.S.N., Ronderos, M.D., Mejia, A., and Malekani, J.M. (2017). Characterization of Monkeypox virus infection in African rope squirrels (Funisciurus sp.). PLoS Negl. Trop. Dis., 11.

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