Iron Oxide Nanoparticles: Green Synthesis and Their Antimicrobial Activity

Author:

Zúñiga-Miranda Johana1ORCID,Guerra Julio2ORCID,Mueller Alexander3ORCID,Mayorga-Ramos Arianna1,Carrera-Pacheco Saskya E.1ORCID,Barba-Ostria Carlos45,Heredia-Moya Jorge1ORCID,Guamán Linda P.1ORCID

Affiliation:

1. Centro de Investigación Biomédica (CENBIO), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito 170527, Ecuador

2. Facultad de Ingeniería en Ciencias Aplicadas, Universidad Técnica del Norte, Ibarra 100107, Ecuador

3. Department of Molecular Biology, Princeton University, Princeton, NJ 08544, USA

4. Escuela de Medicina, Colegio de Ciencias de la Salud Quito, Universidad San Francisco de Quito USFQ, Quito 170901, Ecuador

5. Instituto de Microbiología, Universidad San Francisco de Quito USFQ, Quito 170901, Ecuador

Abstract

The rise of antimicrobial resistance caused by inappropriate use of these agents in various settings has become a global health threat. Nanotechnology offers the potential for the synthesis of nanoparticles (NPs) with antimicrobial activity, such as iron oxide nanoparticles (IONPs). The use of IONPs is a promising way to overcome antimicrobial resistance or pathogenicity because of their ability to interact with several biological molecules and to inhibit microbial growth. In this review, we outline the pivotal findings over the past decade concerning methods for the green synthesis of IONPs using bacteria, fungi, plants, and organic waste. Subsequently, we delve into the primary challenges encountered in green synthesis utilizing diverse organisms and organic materials. Furthermore, we compile the most common methods employed for the characterization of these IONPs. To conclude, we highlight the applications of these IONPs as promising antibacterial, antifungal, antiparasitic, and antiviral agents.

Publisher

MDPI AG

Subject

General Materials Science,General Chemical Engineering

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