The Wild Carrot (Daucus carota): A Phytochemical and Pharmacological Review

Author:

Ismail Jana1ORCID,Shebaby Wassim N.1ORCID,Daher Joey2,Boulos Joelle C.3,Taleb Robin4ORCID,Daher Costantine F.45ORCID,Mroueh Mohamad1

Affiliation:

1. Pharmaceutical Sciences Department, School of Pharmacy, Lebanese American University, Byblos 1102-2801, Lebanon

2. Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Byblos 1102-2801, Lebanon

3. Institute of Pharmacy and Biomedical Sciences, Department of Pharmaceutical Biology, Johannes Gutenberg University, 55128 Mainz, Germany

4. Department of Natural Sciences, School of Arts and Sciences, Lebanese American University, Byblos 1102-2801, Lebanon

5. Alice Ramez Chagoury School of Nursing, Lebanese American University, Byblos 1102-2801, Lebanon

Abstract

Daucus carota L., a member of the Apiaceae family, comprises 13 subspecies, with one being cultivated (D. carota L. ssp. sativus (Hoffm.) Arcang.) and the remaining being wild. Traditionally, the wild carrot has been recognized for its antilithic, diuretic, carminative, antiseptic, and anti-inflammatory properties and has been employed in the treatment of urinary calculus, cystitis, gout, prostatitis, and cancer. While extensive literature is available on the phytochemical, pharmacological, and therapeutic evaluations of the cultivated carrot, limited information has been published on the wild carrot. A thorough search was conducted on the phytochemical composition, folk-medicine uses, and pharmacological properties of wild carrot subspecies (Daucus carota L. ssp. carota). Various electronic databases were consulted, and the literature spanning from 1927 to early 2023 was reviewed. Thirteen wild Daucus carota subspecies were analyzed, revealing over 310 compounds, including terpenoids, phenylpropenoids, flavonoids, and phenolic acids, with 40 constituting more than 3% of the composition. This review also highlights the antioxidant, anticancer, antipyretic, analgesic, antibacterial, antifungal, hypolipidemic, and hepato- and gastroprotective properties of wild carrot subspecies. Existing in vitro and in vivo studies support their traditional uses in treating infections, inflammation, and cancer. However, further research on other subspecies is required to confirm additional applications. Well-designed preclinical and clinical trials are still necessary to establish the safety and efficacy of wild Daucus carota for human use.

Publisher

MDPI AG

Subject

Plant Science,Ecology,Ecology, Evolution, Behavior and Systematics

Reference131 articles.

1. Composition of the essential oil from Daucus carota ssp. carota growing wild in Vienna;Chizzola;J. Essent. Oil-Bear. Plants,2010

2. Essential oils of Daucus carota ssp. maximus;Saad;Pharm. Acta Helv.,1995

3. L’origine de la Carotte et du Radis cultivés;Thellung;J. Agric. Tradit. Bot. Appl.,1927

4. Genetic structure and domestication of carrot (Daucus carota subsp. sativus) (Apiaceae);Iorizzo;Am. J. Bot.,2013

5. (E)-Methylisoeugenol and elemicin: Antibacterial components of Daucus carota L. essential oil against Campylobacter jejuni;Rossi;J. Agric. Food Chem.,2007

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3