Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust—Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques-Reference-Cited by-同舟云学术

Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (Thymus serpyllum L.) Herbal Dust—Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques

Published:2024-03-20 Issue:6 Volume:13 Page:897
ISSN:2223-7747
Container-title:Plants
language:en
Short-container-title:Plants

Author:

Mrkonjić Živan¹^ORCID,Kaplan Muammer²^ORCID,Milošević Sanja¹^ORCID,Božović Danica¹^ORCID,Sknepnek Aleksandra³^ORCID,Miletić Dunja³^ORCID,Lazarević Mrkonjić Ivana¹,Rakić Dušan¹^ORCID,Zeković Zoran¹,Pavlić Branimir¹^ORCID

Affiliation:

1. Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia

2. TUBITAK Marmara Research Centre, Institute of Chemical Technology, P.O. Box 21, 41470 Gebze, Kocaeli, Turkey

3. Faculty of Agriculture, Institute of Food Technology and Biochemistry, University of Belgrade, 11000 Belgrade, Serbia

Abstract

The aim of this study was to provide a chemical profile and determine the antioxidant and antimicrobial activity of the essential oil (EO) and lipid extracts of Thymus serpyllum L. herbal dust obtained via conventional (hydrodistillation (HD) and Soxhlet extraction (SOX)) and novel extraction techniques (supercritical fluid extraction (SFE)). In addition, a comparative analysis of the chemical profiles of the obtained EO and extracts was carried out, as well as the determination of antioxidant, antibacterial and antifungal activity of the lipid extracts. According to the aforementioned antioxidant and antimicrobial activities and the monoterpene yield and selectivity, SFE provided significant advantages compared to the traditional techniques. In addition, SFE extracts could be considered to have great potential in terms of their utilization in the pharmaceutical and cosmetic industries, as well as appropriate replacements for synthetic additives in the food industry.

Funder

Science Fund of the Republic of Serbia

Ministry of Science, Technological Development and Innovations of the Republic of Serbia

Publisher

MDPI AG

Link

https://www.mdpi.com/2223-7747/13/6/897/pdf

Reference48 articles.

1. Influence of harvesting time on composition of the essential oil of Thymus capitatus (L.) Hoffmanns. & Link. growing wild in northern Sicily and its activity on microorganisms affecting historical art crafts;Casiglia;Arab. J. Chem.,2019

2. Thymus spp. plants-Food applications and phytopharmacy properties;Salehi;Trends Food Sci. Technol.,2019

3. Zarzuelo, A., and Crespo, E. (2002). Thyme, CRC Press.

4. The application of medicinal plants in traditional and modern medicine: A review of Thymus vulgaris;Hosseinzadeh;Int. J. Clin. Med.,2015

5. Review of ethnobotanical, phytochemical, and pharmacological study of Thymus serpyllum L.;Evid.-Based Complement. Altern. Med.,2015